Inorganic Chemistry (03) Limit Test for Chlorides | Chloride Limit Test | What is Limit Test
Download the "Solution Pharmacy" Mobile App to Get All Uploaded Notes, Model Question Papers, Answer Papers, Online Tests and other GPAT Materials - https://play.google.com/store/apps/de...
Contents for 1st Unit of Inorganic Chemistry -
Impurities in pharmaceutical substances: History of
Pharmacopoeia, Sources and types of impurities, principles involved in the
limit test for Chloride, Sulphate, Iron, Arsenic, Lead and Heavy metals,
modified limit test for Chloride and Sulphate
LIMIT TESTS
1. LIMIT TEST FOR CHLORIDES
Apparatus Required
Nessler cylinders
Glass rod
Stand
Chemicals Required
Dilute Nitric acid (10%)
Silver nitrate (5%)
Sodium chloride
Principle
It is based upon the chemical reaction between silver nitrate and soluble chlorides in presence of dilute nitric acid to give opalescence of silver chloride. If the Opalescence produced is compared with the standard solution. If the opalescence in the sample is less than the standard, it passes the test. If it is more than the standard, it fails the test.
Procedure
Test sample
1.Specific weight of compound is dissolved in water or solution is prepared as directed in the pharmacopoeia and transferred in Nessler cylinder
2. Add 1ml of nitric acid
3. Dilute to 50ml in Nessler cylinder
4. Add 1ml of AgNO3 solution
5. Keep aside for 5 min
6. Observe the Opalescence/Turbidity
Standard compound
1. Take 1ml of 0.05845 % W/V solution of sodium chloride in Nessler cylinder
2. Add 1ml of nitric acid
3. Dilute to 50ml in Nessler cylinder
4. Add 1ml of AgNO3 solution
5. Keep aside for 5 min
6. Observe the Opalescence/Turbidity
Get in touch with the solution by just clicking the following links-
Facebook Group- / solutionpharamcy
Mobile App - https://play.google.com/store/apps/de...
New Channel (Pharmacy Dictionary) / @pharmacydictionary
E-Mail for official and other work - [email protected]
#solutionpharmacy #Pharmacologyclass #Pharmacognosyvideos #GPAT