Aug 30 2024 This Week in Cardiology
From ESC: post-MI beta blockers, a new therapy for ATTR-CM, holding RASi before non-cardiac surgery, good news in HFpEF, and an ESC preview are the topics John Mandrola, MD, covers this week.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. ABYSS
• ABYSS trial https://www.nejm.org/doi/full/10.1056...
• REDUCE AMI https://www.nejm.org/doi/full/10.1056...
II. ATTR -CM HELIOS B
Positive Top Line Results for Vutrisiran in Cardiac Amyloidosis
https://www.medscape.com/viewarticle/...
• HELIOS A https://www.tandfonline.com/doi/full/...
• HELIOS B https://www.nejm.org/doi/full/10.1056...
III. STOP or NOT Trial
• Observational Study Showing Benefits of Holding RASi https://doi.org/10.1097/ALN.000000000...
• STOP or NOT Protocol Paper -- https://trialsjournal.biomedcentral.c...
• JAMA STOP or NOT https://jamanetwork.com/journals/jama...
IV. GLP1a in HFpEF
The GLP-1 Agonist Semaglutide in HFpEF Cleared a Low Bar https://www.medscape.com/viewarticle/...
• STEP-HFpEF https://www.nejm.org/doi/full/10.1056...
• STEP-HFpEF-DM https://www.nejm.org/doi/full/10.1056...
• SELECT https://www.nejm.org/doi/full/10.1056...
• FLOW https://www.nejm.org/doi/full/10.1056...
• Lancet Meta-analysis https://doi.org/10.1016/S0140-6736(24...
V. ESC Preview
Mandrola's Five Big Trials to Look for at ESC 2024
https://www.medscape.com/viewarticle/...
Topline Finerenone Results Point to Advance in Heart Failure
https://www.medscape.com/viewarticle/...
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